A convenient synthesis of 3-keto bile acids by selective oxidation of bile acids with silver carbonate-Celite.
نویسندگان
چکیده
منابع مشابه
Bile acids: regulation of synthesis.
Bile acids are physiological detergents that generate bile flow and facilitate intestinal absorption and transport of lipids, nutrients, and vitamins. Bile acids also are signaling molecules and inflammatory agents that rapidly activate nuclear receptors and cell signaling pathways that regulate lipid, glucose, and energy metabolism. The enterohepatic circulation of bile acids exerts important ...
متن کاملA Synthesis of Conjugated Bile Acids
In 1916 Wieland and Sorge (1) first described the formation of addition compounds of desoxycholic acid with fatty acids, and suggested the possible importance of this “choleic acid principle” in furthering the absorption of fatty acids and other substances from the intestinal canal. In human bile, however, desoxycholic acid is united with glycine and taurine; hence it is of considerable importa...
متن کاملSelective Oxidation of Xylenes to Toluic Acids
A mixture of manganese, cobalt and lead para-amino benzoates supported on silica gel is used to catalyze oxidation of xylenes to toluic acids in presence of oxygen or air. Reactions are clean and catalysts can be recovered easily and reused.
متن کاملVulnerability of keto bile acids to alkaline hydrolysis.
Rigorous alkaline hydrolysis of the two primary (cholic and chenodeoxycholic) and of the two preponderant secondary (deoxycholic and lithocholic) bile acids found in bile led to excellent recoveries. Such was not the case with 11 different keto bile acid standards. Recoveries for a number of standards were unacceptably low and a variety of artefactural products were tentatively identified by ga...
متن کامل[Bile acids].
Airaudo ChB, Gayte-Sorbier A, Aujoulat P and Mercier V (1988) Thin-layer chromatography of amine antioxidants and antiozonants used in elastomers. Journal of Chromatography 437: 59}82. FateH r Z, Tasi G, Szabady B and Nyiredy Sz (1998) IdentiRcation of amphetamine derivatives by uni-dimensional multiple development and two-dimensional HPTLC combined with postchromatographic derivatization. Jour...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Journal of Lipid Research
سال: 1978
ISSN: 0022-2275
DOI: 10.1016/s0022-2275(20)40722-9